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Begreppsinformation

Föredragen term

Diphtheria Toxin  

Typ

  • Topical Descriptor

Hänvisningstermer

  • Corynebacterium Diphtheriae Toxin
  • Toxin, Corynebacterium Diphtheriae

Anmärkning

  • /antag permitted but consider also DIPHTHERIA ANTITOXIN

Användningsanmärkning

  • An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains MONO(ADP-RIBOSE) TRANSFERASES which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.

Termer på andra språk

URI

http://www.yso.fi/onto/mesh/D004167

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RDF/XML TURTLE JSON-LD Skapad 1999-01-01, senast editerad 2007-07-09