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Begreppsinformation

Föredragen term

Proto-Oncogene Proteins c-abl  

Typ

  • Topical Descriptor

Underordnade begrepp

Hänvisningstermer

  • abl Proto Oncogene Products
  • abl Proto-Oncogene Products
  • abl Proto Oncogene Proteins
  • abl Proto-Oncogene Proteins
  • abl, Proto-Oncogene Proteins
  • c abl Proteins
  • c-abl Proteins
  • Products, abl Proto-Oncogene
  • Proteins abl, Proto-Oncogene
  • Proto-Oncogene Products, abl
  • Proto Oncogene Proteins abl
  • Proto-Oncogene Proteins abl
  • Proto-Oncogene Proteins, abl

Användningsanmärkning

  • Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.

Anmärkning om ändringshistoria

  • 91

Termer på andra språk

URI

http://www.yso.fi/onto/mesh/D016315

Ladda ned detta begrepp:

RDF/XML TURTLE JSON-LD Skapad 1990-06-19, senast editerad 2022-04-11