Begreppsinformation
Föredragen term
Neuropilin-1
Typ
-
Topical Descriptor
Överordnat begrepp
Hänvisningstermer
- A5 Antigen
- Antigen, A5
- Npn 1 Protein
- Npn-1 Protein
- NRP1 Protein
- Receptor, Sema III
- Sema III Receptor
- Semaphorin III Receptor
Användningsanmärkning
- A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
Anmärkning om ändringshistoria
- 2003; use NEUROPILIN-1 (NM) 1991-2002
Termer på andra språk
-
finska
-
svenska
URI
http://www.yso.fi/onto/mesh/D039942
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