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Begreppsinformation

Föredragen term

Neuropilin-1  

Typ

  • Topical Descriptor

Överordnat begrepp

Hänvisningstermer

  • A5 Antigen
  • Antigen, A5
  • Npn 1 Protein
  • Npn-1 Protein
  • NRP1 Protein
  • Receptor, Sema III
  • Sema III Receptor
  • Semaphorin III Receptor

Användningsanmärkning

  • A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.

Anmärkning om ändringshistoria

  • 2003; use NEUROPILIN-1 (NM) 1991-2002

Termer på andra språk

URI

http://www.yso.fi/onto/mesh/D039942

Ladda ned detta begrepp:

RDF/XML TURTLE JSON-LD Skapad 2002-07-03, senast editerad 2022-04-11