Begreppsinformation
Föredragen term
Mad2 Proteins
Typ
-
Topical Descriptor
Överordnat begrepp
Hänvisningstermer
- Mad2 Mitotic Arrest Deficient-like 1 Proteins
Användningsanmärkning
- Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.
Anmärkning om ändringshistoria
- 2014
Termer på andra språk
-
finska
-
svenska
URI
http://www.yso.fi/onto/mesh/D064246
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